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Development of a rapid DNA screening procedure for the Factor V Leiden mutation

Aim—To develop a rapid, simple and highly specific DNA screening procedure based on the amplification refractory mutation system (ARMS) to detect the Leiden mutation in whole blood. Methods—ARMS PCR amplification primers with additional mismatches at either -2 or -3, which greatly improves specifici...

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Dades bibliogràfiques
Publicat a:Clin Mol Pathol
Autors principals: Scobie, G A, Ho, S T, Dolan, G., Kalsheker, N A
Format: Artigo
Idioma:Inglês
Publicat: BMJ Publishing Group 1996
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC408088/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/16696104/
https://ncbi.nlm.nih.govhttps://doi.org/10.1136/mp.49.6.m361
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