Activation of the Ubiquitin Proteasome Pathway in a Mouse Model of Inflammatory Myopathy: A Potential Therapeutic Target

OBJECTIVE: Myositis is characterized by severe muscle weakness. We and others have previously shown that endoplasmic reticulum (ER) stress plays a role in the pathogenesis of myositis. The present study was undertaken to identify perturbed pathways and assess their contribution to muscle disease in...

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Autori principali: Rayavarapu, Sree, Coley, William, der Meulen, Jack H. Van, Cakir, Erdinc, Tappeta, Kathyayini, Kinder, Travis B., Dillingham, Blythe C., Brown, Kristy J., Hathout, Yetrib, Nagaraju, Kanneboyina
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4080828/
https://ncbi.nlm.nih.gov/pubmed/24022788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.38180
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