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ALCOHOL MODULATION OF MMP AND TIMP EXPRESSION IN THE HEART FAVORS COLLAGEN ACCUMULATION

BACKGROUND: Chronic alcohol consumption has been shown in human and animal studies to result in collagen accumulation, myocardial fibrosis, and heart failure. Cardiac fibroblasts produce collagen and regulate extracellular matrix (ECM) homeostasis through the synthesis and activity of matrix metallo...

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Detalhes bibliográficos
Main Authors: El Hajj, E.C., El hajj, M.C., Voloshenyuk, T.G., Mouton, A.J., Khoutorova, E., Molina, P.E., Gilpin, N.W., Gardner, J.D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4080812/
https://ncbi.nlm.nih.gov/pubmed/24033327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acer.12239
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