Mutations in the MSH3 gene preferentially lead to deletions within tracts of simple repetitive DNA in Saccharomyces cerevisiae.

Eukaryotic genomes contain tracts of DNA in which a single base or a small number of bases are repeated (microsatellites). Mutations in the yeast DNA mismatch repair genes MSH2, PMS1, and MLH1 increase the frequency of mutations for normal DNA sequences and destabilize microsatellites. Mutations of...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Strand, M, Earley, M C, Crouse, G F, Petes, T D
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1995
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC40808/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7479796/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.22.10418
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