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Thyroid autoimmunity and ophthalmopathy related to melanoma biologic therapy
Ipilimumab is a fully human monoclonal antibody against Cytotoxic TLymphocyte Antigen 4 (CTLA-4). CTLA-4 negatively regulates immune cell activation. In patients with metastatic melanoma, ipilimumab increases survival time and induces complete remission in some patients. However, immune related adve...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4080629/ https://ncbi.nlm.nih.gov/pubmed/21088057 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/EJE-10-0833 |
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