Mice Deficient in Intestinal Epithelium Cytochrome P450 Reductase are Prone to Acute Toxin-induced Mucosal Damage

Cytochrome P450 (P450) enzymes are a superfamily of heme-containing enzymes involved in the metabolism of various endogenous compounds, including retinoids, glucocorticoids, and eicosanoids, that are postulated to participate in the maintenance and/or development of inflammatory and immune reactions...

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Main Authors: Ahlawat, Sarita, Xie, Fang, Zhu, Yi, D'Hondt, Rebecca, Ding, Xinxin, Zhang, Qing-Yu, Mantis, Nicholas J.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2014
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4080431/
https://ncbi.nlm.nih.gov/pubmed/24989705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep05551
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