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Effects of genetic and early environmental risk factors for depression on serotonin transporter expression and methylation profiles

The serotonin transporter (SERT) gene-linked polymorphic region (5-HTTLPR) has been implicated in moderating the link between life stress and depression. However, respective molecular pathways of gene–environment (GxE) interaction are largely unknown. Sustained alterations in SERT gene expression pr...

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Detalhes bibliográficos
Main Authors: Wankerl, M, Miller, R, Kirschbaum, C, Hennig, J, Stalder, T, Alexander, N
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4080318/
https://ncbi.nlm.nih.gov/pubmed/24937096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tp.2014.37
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