Growth arrest and forced differentiation of human primary glioblastoma multiforme by a novel small molecule

Glioblastoma multiforme is the most common malignant brain tumor in adults, with an average survival of less than one year due to its resistance to therapy. Recent studies reported that GBM initiates from CD133-expressing cancer stem cells (CSC). However, the efficacy of CSC targeting is limited. A...

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Detalhes bibliográficos
Main Authors: Kang, Tae-Wook, Choi, Soon Won, Yang, Se-Ran, Shin, Tae-Hoon, Kim, Hyung-Sik, Yu, Kyung-Rok, Hong, In-Sun, Ro, Seonggu, Cho, Joong Myung, Kang, Kyung-Sun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4080225/
https://ncbi.nlm.nih.gov/pubmed/24989033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep05546
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