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Dissection of thousands of cell type-specific enhancers identifies dinucleotide repeat motifs as general enhancer features

Gene expression is determined by genomic elements called enhancers, which contain short motifs bound by different transcription factors (TFs). However, how enhancer sequences and TF motifs relate to enhancer activity is unknown, and general sequence requirements for enhancers or comprehensive sets o...

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Detalhes bibliográficos
Main Authors: Yáñez-Cuna, J. Omar, Arnold, Cosmas D., Stampfel, Gerald, Boryń, Łukasz M., Gerlach, Daniel, Rath, Martina, Stark, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4079970/
https://ncbi.nlm.nih.gov/pubmed/24714811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.169243.113
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