GWAS identifies an NAT2 acetylator status tag single nucleotide polymorphism to be a major locus for skin fluorescence

AIMS/HYPOTHESIS: Skin fluorescence (SF) is a non-invasive marker of AGEs and is associated with the long-term complications of diabetes. SF increases with age and is also greater among individuals with diabetes. A familial correlation of SF suggests that genetics may play a role. We therefore perfor...

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Main Authors: Eny, Karen M., Lutgers, Helen L., Maynard, John, Klein, Barbara E. K., Lee, Kristine E., Atzmon, Gil, Monnier, Vincent M., van Vliet-Ostaptchouk, Jana V., Graaff, Reindert, van der Harst, Pim, Snieder, Harold, van der Klauw, Melanie M., Sell, David R., Hosseini, S. Mohsen, Cleary, Patricia A., Braffett, Barbara H., Orchard, Trevor J., Lyons, Timothy J., Howard, Kerri, Klein, Ronald, Crandall, Jill P., Barzilai, Nir, Milman, Sofiya, Ben-Avraham, Danny, Wolffenbuttel, Bruce H. R., Paterson, Andrew D.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4079945/
https://ncbi.nlm.nih.gov/pubmed/24934506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-014-3286-9
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