COMT Val158Met, but not BDNF Val66Met, is associated with white matter abnormalities of the temporal lobe in patients with first-episode, treatment-naïve major depressive disorder: a diffusion tensor imaging study

We investigated the association between the Val158Met polymorphism of the catechol-O-methyltransferase (COMT) gene, the Val66Met polymorphism of the brain-derived neurotrophic factor (BDNF) gene, and white matter changes in patients with major depressive disorder (MDD) and healthy subjects using dif...

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Main Authors: Hayashi, Kenji, Yoshimura, Reiji, Kakeda, Shingo, Kishi, Taro, Abe, Osamu, Umene-Nakano, Wakako, Katsuki, Asuka, Hori, Hikaru, Ikenouchi-Sugita, Atsuko, Watanabe, Keita, Ide, Satoru, Ueda, Issei, Moriya, Junji, Iwata, Nakao, Korogi, Yukunori, Kubicki, Marek, Nakamura, Jun
Formato: Artigo
Idioma:Inglês
Publicado: Dove Medical Press 2014
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Original Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4079817/
https://ncbi.nlm.nih.gov/pubmed/25061303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/NDT.S61275
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