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Novel Gut-Based Pharmacology of Metformin in Patients with Type 2 Diabetes Mellitus

Metformin, a biguanide derivate, has pleiotropic effects beyond glucose reduction, including improvement of lipid profiles and lowering microvascular and macrovascular complications associated with type 2 diabetes mellitus (T2DM). These effects have been ascribed to adenosine monophosphate-activated...

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Detalhes bibliográficos
Main Authors: Napolitano, Antonella, Miller, Sam, Nicholls, Andrew W., Baker, David, Van Horn, Stephanie, Thomas, Elizabeth, Rajpal, Deepak, Spivak, Aaron, Brown, James R., Nunez, Derek J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4079657/
https://ncbi.nlm.nih.gov/pubmed/24988476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0100778
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