Effect of vasopressin antagonism on renal handling of sodium and water and central and brachial blood pressure during inhibition of the nitric oxide system in healthy subjects

BACKGROUND: Tolvaptan is a selective vasopressin receptor antagonist (V2R) that increases free water excretion. We wanted to test the hypotheses that tolvaptan changes both renal handling of water and sodium and systemic hemodynamics during basal conditions and during nitric oxide (NO)-inhibition wi...

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Detalhes bibliográficos
Main Authors: Al Therwani, Safa, Mose, Frank Holden, Jensen, Janni Majgaard, Bech, Jesper Nørgaard, Pedersen, Erling Bjerregaard
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4079642/
https://ncbi.nlm.nih.gov/pubmed/24965902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2369-15-100
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