Effect of vasopressin antagonism on renal handling of sodium and water and central and brachial blood pressure during inhibition of the nitric oxide system in healthy subjects

BACKGROUND: Tolvaptan is a selective vasopressin receptor antagonist (V2R) that increases free water excretion. We wanted to test the hypotheses that tolvaptan changes both renal handling of water and sodium and systemic hemodynamics during basal conditions and during nitric oxide (NO)-inhibition wi...

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Détails bibliographiques
Auteurs principaux: Al Therwani, Safa, Mose, Frank Holden, Jensen, Janni Majgaard, Bech, Jesper Nørgaard, Pedersen, Erling Bjerregaard
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2014
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4079642/
https://ncbi.nlm.nih.gov/pubmed/24965902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2369-15-100
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