Procyanidin B2 3,3″-di-O-gallate, a biologically active constituent of grape seed extract, induces apoptosis in human prostate cancer cells via targeting NF-κB, Stat3 and AP1 transcription factors

Recently, we identified procyanidin B2 3,3″-di-O-gallate (B2G2) as most active constituent of grape seed extract (GSE) for efficacy against prostate cancer (PCa). Isolating large quantities of B2G2 from total GSE is labor intensive and expensive, thereby limiting both efficacy and mechanistic studie...

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Hauptverfasser: Tyagi, Alpna, Raina, Komal, Shrestha, Suraj Prakash, Miller, Bettina, Thompson, John A., Wempe, Michael F., Agarwal, Rajesh, Agarwal, Chapla
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4079462/
https://ncbi.nlm.nih.gov/pubmed/24191894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/01635581.2013.783602
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