GTS-21, an α7-nicotinic acetylcholine receptor agonist, modulates Th1 differentiation in CD4(+) T cells from patients with rheumatoid arthritis

GTS-21 (also known as DMBX-anabaseine), a selective α7 nicotinic acetylcholine receptor (α7nAChR) agonist, has previously been found to inhibit the inflammation associated with rheumatoid arthritis (RA). RA is an autoimmune disease, where an abnormal immune system plays a critical role in the occurr...

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Main Authors: WU, SHIYAO, ZHAO, HONGJUN, LUO, HUI, XIAO, XIANZHONG, ZHANG, HUALI, LI, TONG, ZUO, XIAOXIA
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2014
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4079428/
https://ncbi.nlm.nih.gov/pubmed/25009619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2014.1754
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