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Construction and verification of the targeted uPA-shRNA lentiviral vector and evaluation of the transfection and silencing rate
Urokinase-type plasminogen activator (uPA) receptors, which are released by the synovial tissue, are responsible for the activation of cartilage-breakdown proteases and play critical roles in cartilage degradation during the progression of osteoarthritis (OA). RNA interference (RNAi) technology has...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
D.A. Spandidos
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4079424/ https://ncbi.nlm.nih.gov/pubmed/25009597 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2014.1741 |
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