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The effects of fucodian on senescence are controlled by the p16(INK4a)-pRb and p14(Arf)-p53 pathways in hepatocellular carcinoma and hepatic cell lines

Fucoidan is known to have various pharmacological effects, including antitumor activity. Although it has potential as a therapeutic agent for cancer cells, the anti-senescence effects and detailed mechanism of action remain poorly understood in normal hepatic cells. We investigated the anticancer fu...

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Main Authors: MIN, EUN-YOUNG, KIM, IN-HYE, LEE, JUNGIM, KIM, EUN-YOUNG, CHOI, YOUN-HEE, NAM, TAEK-JEONG
格式: Artigo
語言:Inglês
出版: D.A. Spandidos 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4079163/
https://ncbi.nlm.nih.gov/pubmed/24807532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2014.2426
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