A mutation in POLE predisposing to a multi-tumour phenotype

Somatic mutations in the POLE gene encoding the catalytic subunit of DNA polymerase ɛ have been found in sporadic colorectal cancers (CRCs) and are most likely of importance in tumour development and/or progression. Recently, families with dominantly inherited colorectal adenomas and colorectal canc...

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Detalhes bibliográficos
Main Authors: ROHLIN, ANNA, ZAGORAS, THEOFANIS, NILSSON, STAFFAN, LUNDSTAM, ULF, WAHLSTRÖM, JAN, HULTÉN, LEIF, MARTINSSON, TOMMY, KARLSSON, GÖRAN B., NORDLING, MARGARETA
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2014
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4079162/
https://ncbi.nlm.nih.gov/pubmed/24788313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2014.2410
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