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The copper chelator ATN-224 induces caspase-independent cell death in diffuse large B cell lymphoma
Bcl-2 and other anti-apoptotic proteins are associated with defective caspase-dependent apoptotic pathways, resulting in chemoresistance. We have previously shown that ATN-224, a copper chelator drug, induces cell death in murine thymic lymphoma cells transfected with Bcl-2. In the current study, we...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
D.A. Spandidos
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4079159/ https://ncbi.nlm.nih.gov/pubmed/24788952 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2014.2396 |
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