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Loss of Purkinje Cells in the PKCγ H101Y Transgenic Mouse

Spinocerebellar ataxia type 14 (SCA14) is an autosomal, dominant neurodegenerative disorder caused by mutations in PKCγ. The objective of this study was to determine effects of PKCγ H101Y SCA14 mutation on Purkinje cells in the transgenic mouse. Results demonstrated that wild type PKCγ-like Purkinje...

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Detalhes bibliográficos
Main Authors: Zhang, Yunong, Snider, Adam, Willard, Lloyd, Takemoto, Dolores J, Lin, Dingbo
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4079109/
https://ncbi.nlm.nih.gov/pubmed/19056342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2008.11.082
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