Estrogen receptor α mediates the nongenomic activation of endothelial nitric oxide synthase by estrogen

Estrogen is an important vasoprotective molecule that causes the rapid dilation of blood vessels by activating endothelial nitric oxide synthase (eNOS) through an unknown mechanism. In studies of intact ovine endothelial cells, 17β-estradiol (E(2)) caused acute (five-minute) activation of eNOS that...

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Autores principales: Chen, Zhong, Yuhanna, Ivan S., Galcheva-Gargova, Zoya, Karas, Richard H., Mendelsohn, Michael E., Shaul, Philip W.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 1999
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC407904/
https://ncbi.nlm.nih.gov/pubmed/9927501
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