Biologic significance of angiopoietin-2 expression in human hepatocellular carcinoma

Human hepatocellular carcinoma (HCC) is generally a highly vascular tumor, but the mechanisms of neovascularization that permit rapid growth have not been defined. Angiopoietins (Ang) recently have been identified as ligands for vascular endothelial-specific Tie2 receptor tyrosine kinase and may be...

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Pubblicato in:J Clin Invest
Autori principali: Tanaka, Shinji, Mori, Masaki, Sakamoto, Yoshihiro, Makuuchi, Masatoshi, Sugimachi, Keizo, Wands, Jack R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 1999
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Article
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC407900/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9927494/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI4891
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