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CK1 is required for a mitotic checkpoint that delays cytokinesis
Failure to accurately partition genetic material during cell division causes aneuploidy and drives tumorigenesis [1]. Cell cycle checkpoints safeguard cells from such catastrophes by impeding cell cycle progression when mistakes arise. FHA-RING E3 ligases, including human RNF8 [2] and CHFR [3] and f...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4078987/ https://ncbi.nlm.nih.gov/pubmed/24055157 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2013.07.077 |
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