Glucocorticoids enhance acid activation of the Na(+)/H(+) exchanger 3 (NHE3)

In the absence of exogenous glucocorticoids, decreasing media pH (from 7.4 to 6.8) for 24 hours increased the Na(+)/H(+) exchanger 3 (NHE3) activity in opossum kidney (OKP) cells. 10(–7) M and 10(–8) M hydrocortisone increased NHE3 activity, and in their presence, acid incubation further increased N...

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Hauptverfasser: Ambühl, Patrice M., Yang, Xiaojing, Peng, Yan, Preisig, Patricia A., Moe, Orson W., Alpern, Robert J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 1999
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC407891/
https://ncbi.nlm.nih.gov/pubmed/9927505
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