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Perilipins 2 and 3 lack a carboxy-terminal domain present in perilipin 1 involved in sequestering ABHD5 and suppressing basal lipolysis

Lipid droplets (LDs) are a conserved feature of most organisms. Vertebrate adipocytes have evolved to efficiently store and release lipids for the whole organism from a single droplet. Perilipin 1, the most abundant lipid-coat protein in adipocytes, plays a key role in regulating lipolysis. In other...

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Detalhes bibliográficos
Main Authors: Patel, Satish, Yang, Wei, Kozusko, Kristina, Saudek, Vladimir, Savage, David B.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4078844/
https://ncbi.nlm.nih.gov/pubmed/24927580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1318791111
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