ロード中...
Targeting c-MYC by antagonizing PP2A inhibitors in breast cancer
The transcription factor c-MYC is stabilized and activated by phosphorylation at serine 62 (S62) in breast cancer. Protein phosphatase 2A (PP2A) is a critical negative regulator of c-MYC through its ability to dephosphorylate S62. By inactivating c-MYC and other key signaling pathways, PP2A plays an...
保存先:
| 主要な著者: | , , , , , , , , |
|---|---|
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2014
|
| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4078832/ https://ncbi.nlm.nih.gov/pubmed/24927563 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1317630111 |
| タグ: |
タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!
|