Chem-seq permits identification of genomic targets of drugs against androgen receptor regulation selected by functional phenotypic screens

Understanding the mechanisms by which compounds discovered using cell-based phenotypic screening strategies might exert their effects would be highly augmented by new approaches exploring their potential interactions with the genome. For example, altered androgen receptor (AR) transcriptional progra...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Jin, Chunyu, Yang, Liuqing, Xie, Min, Lin, Chunru, Merkurjev, Daria, Yang, Joy C., Tanasa, Bogdan, Oh, Soohwan, Zhang, Jie, Ohgi, Kenneth A., Zhou, Hongyan, Li, Wenbo, Evans, Christopher P., Ding, Sheng, Rosenfeld, Michael G.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: National Academy of Sciences 2014
Θέματα:
Biological Sciences
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4078819/
https://ncbi.nlm.nih.gov/pubmed/24928520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1404303111
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