The plasminogen activation system enhances brain and heart invasion in murine relapsing fever borreliosis

The role of the plasminogen activation system (PAS) was investigated during the course of infection of a relapsing fever Borrelia species in plasminogen-deficient (plg( –/–)) and control (plg (+/+) and plg (+/–)) mice. Subcutaneous inoculation of 10(4) spirochetes resulted in a peak spirochetemia fi...

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Bibliographic Details

Published in:	J Clin Invest
Main Authors:	Gebbia, Joseph A., Monco, Juan Carlos Garcia, Degen, Jay L., Bugge, Thomas H., Benach, Jorge L.
Format:	Artigo
Language:	Inglês
Published:	American Society for Clinical Investigation 1999
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC407868/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9884337/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI5171
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