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NADPH oxidases regulate cell growth and migration in myeloid cells transformed by oncogenic tyrosine kinases
Transformation by tyrosine kinase oncogenes in myeloid malignancies, including BCR-ABL in chronic myeloid leukemia, FLT3ITD in acute myeloid leukemia (AML) or JAK2V617F in myeloproliferative neoplasms (MPN), is associated with increased growth and cytoskeletal abnormalities. Using targeted approache...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4078661/ https://ncbi.nlm.nih.gov/pubmed/21072051 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2010.263 |
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