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Decreased angiogenesis and arthritic disease in rabbits treated with an αvβ3 antagonist

Rheumatoid arthritis (RA) is an inflammatory disease associated with intense angiogenesis and vascular expression of integrin αvβ3. Intra-articular administration of a cyclic peptide antagonist of integrin αvβ3 to rabbits with antigen-induced arthritis early in disease resulted in inhibition of syno...

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Dettagli Bibliografici
Pubblicato in:J Clin Invest
Autori principali: Storgard, Chris M., Stupack, Dwayne G., Jonczyk, Alfred, Goodman, Simon L., Fox, Robert I., Cheresh, David A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 1999
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC407856/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9884333/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI3756
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