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The RNA-dependent RNA polymerase, QDE-1, is a rate-limiting factor in post-transcriptional gene silencing in Neurospora crassa

The RNA-dependent RNA polymerase (RdRP) qde-1 is an essential component of post-transcriptional gene silencing (PTGS), termed ‘quelling’ in the fungus Neurospora crassa. Here we show that the overexpression of QDE-1 results in a dramatic increase in the efficiency of quelling, with a concomitant net...

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Bibliografski detalji
Glavni autori: Forrest, Emma C., Cogoni, Carlo, Macino, Giuseppe
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2004
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC407816/
https://ncbi.nlm.nih.gov/pubmed/15090622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh530
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