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Mitochondrial reactive oxygen species accelerate the expression of heme carrier protein 1 and enhance photodynamic cancer therapy effect

Photodynamic therapy using hematoporphyrin and its derivatives is clinically useful for cancer treatments. It has been reported that cancer cells incorporate hematoporphyrin and its derivatives via heme carrier protein 1, which is a proton-coupled folate transporter. However, the mechanism of this p...

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Detalhes bibliográficos
Main Authors: Ito, Hiromu, Matsui, Hirofumi, Tamura, Masato, Majima, Hideyuki J., Indo, Hiroko P., Hyodo, Ichinosuke
Formato: Artigo
Idioma:Inglês
Publicado em: the Society for Free Radical Research Japan 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4078070/
https://ncbi.nlm.nih.gov/pubmed/25120282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3164/jcbn.14-27
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