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Mitochondrial reactive oxygen species accelerate the expression of heme carrier protein 1 and enhance photodynamic cancer therapy effect

Photodynamic therapy using hematoporphyrin and its derivatives is clinically useful for cancer treatments. It has been reported that cancer cells incorporate hematoporphyrin and its derivatives via heme carrier protein 1, which is a proton-coupled folate transporter. However, the mechanism of this p...

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Главные авторы: Ito, Hiromu, Matsui, Hirofumi, Tamura, Masato, Majima, Hideyuki J., Indo, Hiroko P., Hyodo, Ichinosuke
Формат: Artigo
Язык:Inglês
Опубликовано: the Society for Free Radical Research Japan 2014
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4078070/
https://ncbi.nlm.nih.gov/pubmed/25120282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3164/jcbn.14-27
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