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Spexin is a Novel Human Peptide that Reduces Adipocyte Uptake of Long Chain Fatty Acids and Causes Weight Loss in Rodents with Diet-induced Obesity()

OBJECTIVE: Microarray studies identified Ch12:orf39 (Spexin) as the most dysregulated gene in obese human fat. Therefore we examined its role in obesity pathogenesis. DESIGN AND METHODS: Spexin effects on food intake, meal patterns, body weight, Respiratory Exchange Ratio (RER), and locomotor activi...

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Detalhes bibliográficos
Main Authors: Walewski, José L., Ge, Fengxia, Lobdell, Harrison, Levin, Nancy, Schwartz, Gary J., Vasselli, Joseph, Pomp, Afons, Dakin, Gregory, Berk, Paul D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4077920/
https://ncbi.nlm.nih.gov/pubmed/24550067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/oby.20725
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