Crystal structure of the I-domain from the CD11a/CD18 (LFA-1, alpha L beta 2) integrin.
We report the 1.8-A crystal structure of the CD11a I-domain with bound manganese ion. The CD11a I-domain contains binding sites for intercellular adhesion molecules 1 and 3 and can exist in both low- and high-affinity states. The metal-bound form reported here is likely to represent a high-affinity...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1995
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC40779/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7479767/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.22.10277 |
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