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Dual therapeutic benefit of electroporation-mediated DNA vaccination in vivo: Enhanced gene transfer and adjuvant activity

DNA vaccination consists of administering an antigen-coding nucleotide sequence. In order to improve the efficacy of DNA vaccines, electroporation is one of the most commonly used methods to enhance DNA uptake. Here, we discuss additional immunological effects of electroporation that are key aspects...

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Bibliografiska uppgifter
Huvudupphovsmän: Calvet, Christophe Y, André, Franck M, Mir, Lluis M
Materialtyp: Artigo
Språk:Inglês
Publicerad: Landes Bioscience 2014
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4077865/
https://ncbi.nlm.nih.gov/pubmed/25050220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.28540
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