Genomic Responses during Acute Human Anaphylaxis Are Characterized by Upregulation of Innate Inflammatory Gene Networks

BACKGROUND: Systemic spread of immune activation and mediator release is required for the development of anaphylaxis in humans. We hypothesized that peripheral blood leukocyte (PBL) activation plays a key role. OBJECTIVE: To characterize PBL genomic responses during acute anaphylaxis. METHODS: PBL s...

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Detalhes bibliográficos
Main Authors: Stone, Shelley F., Bosco, Anthony, Jones, Anya, Cotterell, Claire L., van Eeden, Pauline E., Arendts, Glenn, Fatovich, Daniel M., Brown, Simon G. A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4077795/
https://ncbi.nlm.nih.gov/pubmed/24983946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0101409
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