Analysis of Altered MicroRNA Expression Profiles in Proximal Renal Tubular Cells in Response to Calcium Oxalate Monohydrate Crystal Adhesion: Implications for Kidney Stone Disease

BACKGROUND: Calcium oxalate monohydrate (COM) is the major crystalline component in kidney stones and its adhesion to renal tubular cells leads to tubular injury. However, COM-induced toxic effects in renal tubular cells remain ambiguous. MicroRNAs (miRNAs) play an important role in gene regulation...

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Main Authors: Wang, Bohan, Wu, Bolin, Liu, Jun, Yao, Weimin, Xia, Ding, Li, Lu, Chen, Zhiqiang, Ye, Zhangqun, Yu, Xiao
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4077747/
https://ncbi.nlm.nih.gov/pubmed/24983625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0101306
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