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Regulation of the JNK3 Signaling Pathway during Islet Isolation: JNK3 and c-fos as New Markers of Islet Quality for Transplantation

Stress conditions generated throughout pancreatic islet processing initiate the activation of pro-inflammatory pathways and beta-cell destruction. Our goal is to identify relevant and preferably beta-specific markers to assess the activation of beta-cell stress and apoptotic mechanisms, and therefor...

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Detalhes bibliográficos
Main Authors: Abdelli, Saida, Papas, Klearchos K., Mueller, Kate R., Murtaugh, Mike P., Hering, Bernhard J., Bonny, Christophe
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4077704/
https://ncbi.nlm.nih.gov/pubmed/24983249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0099796
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