Evaluation of antitumor activity of a TGF-beta receptor I inhibitor (SD-208) on human colon adenocarcinoma

BACKGROUND: Transforming growth factor-β (TGF-β) pathway is involved in primary tumor progression and in promoting metastasis in a considerable proportion of human cancers such as colorectal cancer (CRC). Therefore, blockage of TGF-β pathway signaling via an inhibitor could be a valuable tool in CRC...

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Autori principali: Akbari, Abolfazl, Amanpour, Saeid, Muhammadnejad, Samad, Ghahremani, Mohammad Hossein, Ghaffari, Seyed Hamidollah, Dehpour, Ahmad Reza, Mobini, Gholam Reza, Shidfar, Fatemeh, Abastabar, Mahdi, Khoshzaban, Ahad, Faghihloo, Ebrahim, Karimi, Abbas, Heidari, Mansour
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4077684/
https://ncbi.nlm.nih.gov/pubmed/24902843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2008-2231-22-47
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