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Seeing the forest for the trees: kidney oncogenomes relate to therapeutic outcomes

Renal cell carcinoma is a heterogeneous disease, and tissue investigations provide clues that may predict treatment response. Oncogenomic analysis of five outliers, who achieved a sustained response with rapalogues, implicates alterations of the TSC1 and mTOR genes, and reveals insights into the con...

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Hlavní autoři: Chism, David D., Rathmell, W. Kimryn
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4077661/
https://ncbi.nlm.nih.gov/pubmed/24634386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-14-0056
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