Safety and Immunogenicity of a Live Oral Recombinant Cholera Vaccine VA1.4: A Randomized, Placebo Controlled Trial in Healthy Adults in a Cholera Endemic Area in Kolkata, India

BACKGROUND: A live oral cholera vaccine VA 1.4 developed from a non-toxigenic Vibrio cholerae O1 El Tor strain using ctxB gene insertion was further developed into a clinical product following cGMP and was evaluated in a double-blind randomized placebo controlled parallel group two arm trial with al...

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Detalhes bibliográficos
Main Authors: Kanungo, Suman, Sen, Bandana, Ramamurthy, Thandavarayan, Sur, Dipika, Manna, Byomkesh, Pazhani, Gururaja P., Chowdhury, Goutam, Jhunjhunwala, Puja, Nandy, Ranjan K., Koley, Hemanta, Bhattacharya, Mihir Kumar, Gupta, Sanjay, Goel, Gaurav, Dey, Bindu, M, Thungapathra, Nair, G. Balakrish, Ghosh, Amit, Mahalanabis, Dilip
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4077646/
https://ncbi.nlm.nih.gov/pubmed/24983989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0099381
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