(-)-Epicatechin mitigates high fructose-associated insulin resistance by modulating redox signaling and endoplasmic reticulum stress

We investigated the capacity of dietary (-)-epicatechin (EC) to mitigate insulin resistance through the modulation of redox-regulated mechanisms in a rat model of metabolic syndrome (MetS). Adolescent rats were fed a regular chow diet without or with high fructose (HFr) (10% (w/v)) in drinking water...

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Hauptverfasser: Bettaieb, Ahmed, Vazquez Prieto, Marcela A., Rodriguez Lanzi, Cecilia, Miatello, Roberto M., Haj, Fawaz G., Fraga, César G., Oteiza, Patricia I.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4077617/
https://ncbi.nlm.nih.gov/pubmed/24746618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2014.04.011
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