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Regioselective S(N)2' Mitsunobu reaction of Morita–Baylis–Hillman alcohols: A facile and stereoselective synthesis of α-alkylidene-β-hydrazino acid derivatives

A highly regioselective S(N)2' Mitsunobu reaction between Morita–Baylis–Hillman (MBH) alcohols, azodicarboxylates, and triphenylphosphine is developed, which provides an easy access to α-alkylidene-β-hydrazino acid derivatives in high yields and good stereoselectivity. This reaction represents...

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Autori principali: Xu, Silong, Shang, Jian, Zhang, Junjie, Tang, Yuhai
Natura: Artigo
Lingua:Inglês
Pubblicazione: Beilstein-Institut 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4077529/
https://ncbi.nlm.nih.gov/pubmed/24991249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.10.98
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