Signaling Lymphocyte Activated Molecule (SLAM)/SLAM-associated Protein (SAP) Pathway Regulates Human B-cell Tolerance

BACKGROUND: SAP can mediate the function of SLAM molecules, which have been proposed to be involved in the development of autoimmunity in mice. OBJECTIVE: We sought to determine if the SLAM/SAP pathway regulates the establishment of human B-cell tolerance and what mechanisms of B-cell tolerance coul...

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Main Authors: Menard, Laurence, Cantaert, Tineke, Chamberlain, Nicolas, Tangye, Stuart G., Riminton, Sean, Church, Joseph A., Klion, Amy, Cunninham-Rundles, Charlotte, Nichols, Kim E., Meffre, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4077428/
https://ncbi.nlm.nih.gov/pubmed/24373350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2013.10.051
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