A high-content imaging assay for the quantification of the Burkholderia pseudomallei induced multinucleated giant cell (MNGC) phenotype in murine macrophages

BACKGROUND: Burkholderia pseudomallei (Bp), a Gram-negative, motile, facultative intracellular bacterium is the causative agent of melioidosis in humans and animals. The Bp genome encodes a repertoire of virulence factors, including the cluster 3 type III secretion system (T3SS-3), the cluster 1 typ...

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Detalhes bibliográficos
Main Authors: Pegoraro, Gianluca, Eaton, Brett P, Ulrich, Ricky L, Lane, Douglas J, Ojeda, Jenifer F, Bavari, Sina, DeShazer, David, Panchal, Rekha G
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Methodology Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4077104/
https://ncbi.nlm.nih.gov/pubmed/24750902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2180-14-98
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