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Association Between Foldability and Aggregation Propensity in Small Disulfide-Rich Proteins

Aims: Disulfide-rich domains (DRDs) are small proteins whose native structure is stabilized by the presence of covalent disulfide bonds. These domains are versatile and can perform a wide range of functions. Many of these domains readily unfold on disulfide bond reduction, suggesting that in the abs...

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Detalhes bibliográficos
Main Authors: Fraga, Hugo, Graña-Montes, Ricardo, Illa, Ricard, Covaleda, Giovanni, Ventura, Salvador
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4076991/
https://ncbi.nlm.nih.gov/pubmed/24635049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2013.5543
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