Total Phenytoin concentration is not well correlated with active free drug in critically-ill head trauma patients

OBJECTIVE: Phenytoin is an antiepileptic drug used widely for prophylaxis and treatment of seizure after neurotrauma. Phenytoin has a complex pharmacokinetics and monitoring of its serum concentrations is recommended during treatment. Total phenytoin concentration is routinely measured for monitorin...

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Main Authors: Sadeghi, Kourosh, Hadi, Farin, Ahmadi, Arezoo, Hamishehkar, Hadi, Beigmohammadi, Mohammad-Taghi, Mahmoodpoor, Ata, Rouini, Mohammad Reza, Farhudi, Shirin, Hendoui, Narjes, Najafi, Atabak, Mojtahedzadeh, Mojtaba
Formato: Artigo
Idioma:Inglês
Publicado: Medknow Publications & Media Pvt Ltd 2013
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4076917/
https://ncbi.nlm.nih.gov/pubmed/24991615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/2279-042X.122376
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