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A Bayesian Perspective on Estimation of Variability and Uncertainty in Mechanism-Based Models

Mechanism-based pharmacokinetic/pharmacodynamic models have a fundamental basis in biology and pharmacology and, thus, are useful for hypothesis generation and extrapolation beyond the conditions of the original analysis data. The complexity of these models necessitates the incorporation of prior kn...

Täydet tiedot

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Bibliografiset tiedot
Päätekijä: Leil, T A
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4076806/
https://ncbi.nlm.nih.gov/pubmed/24964283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/psp.2014.19
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