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A reduction in Npas4 expression results in delayed neural differentiation of mouse embryonic stem cells

INTRODUCTION: Npas4 is a calcium-dependent transcription factor expressed within neurons of the brain where it regulates the expression of several genes that are important for neuronal survival and synaptic plasticity. It is known that in the adult brain Npas4 plays an important role in several key...

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Hlavní autoři: Klaric, Thomas S, Thomas, Paul Q, Dottori, Mirella, Leong, Wai Khay, Koblar, Simon A, Lewis, Martin D
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4076635/
https://ncbi.nlm.nih.gov/pubmed/24887558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/scrt453
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