A novel self-lipid antigen targets human T cells against CD1c(+) leukemias

T cells that recognize self-lipids presented by CD1c are frequent in the peripheral blood of healthy individuals and kill transformed hematopoietic cells, but little is known about their antigen specificity and potential antileukemia effects. We report that CD1c self-reactive T cells recognize a nov...

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主要な著者: Lepore, Marco, de Lalla, Claudia, Gundimeda, S. Ramanjaneyulu, Gsellinger, Heiko, Consonni, Michela, Garavaglia, Claudio, Sansano, Sebastiano, Piccolo, Francesco, Scelfo, Andrea, Häussinger, Daniel, Montagna, Daniela, Locatelli, Franco, Bonini, Chiara, Bondanza, Attilio, Forcina, Alessandra, Li, Zhiyuan, Ni, Guanghui, Ciceri, Fabio, Jenö, Paul, Xia, Chengfeng, Mori, Lucia, Dellabona, Paolo, Casorati, Giulia, De Libero, Gennaro
フォーマット: Artigo
言語:Inglês
出版事項: The Rockefeller University Press 2014
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Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4076585/
https://ncbi.nlm.nih.gov/pubmed/24935257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20140410
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